These trials are currently recruiting in sites across New Zealand. The ON TRACK Network aims to support these trials and promotes engagement across sites. There are still opportunities to join these trials, if you would like to become involved please use the contact detail supplied for each trial.

Many of these trials have additional cohort studies which include longer term outcome follow-up studies.


The Diamond Trial


This randomised multi-factorial trial examines the role of different feeding strategies; parenteral nutrition, supplementary milk feeds and sensory stimuli (taste and smell), in infants born moderate- to late-preterm (32-36 weeks gestation) whilst waiting for full enteral nutrition with their mother’s own milk to be established to optimise their growth, metabolic outcomes and development. This trial has been endorsed by the PSANZ IMPACT Network.

Trial Registration: ACTRN12616001199404

Trial website: https://impact.psanz.com.au/clinical-trials/trial-information/

Recruiting Sites: Middlemore Hospital, Auckland City Hospital

Contact for information: Tanith Alexander t.alexander@auckland.ac.nz

Cohort Studies included: No


The GEMS Study 

 

This randomised trial will determine how gestational diabetes mellitus should be diagnosed by comparing two different blood glucose threshold criteria. The trial is recruiting 9000 women in the Auckland region who are pregnant with one baby and less than 34 weeks with no pre-existing diabetes or history of gestational diabetes.

Trial Registration: ACTRN12615000290594

Trial website: http://www.liggins.auckland.ac.nz/en/for/thecommunity/gems-study.html

Recruiting Sites: Middlemore Hospital, Auckland City Hospital

Contact for information: gems@auckland.ac.nz

Cohort Studies included: Yes


The hPOD Study


This randomised placebo-controlled trial compares the use of prophylactic oral dextrose gel with placebo in newborn babies at risk of neonatal hypoglycaemia aiming to prevent hypoglycaemia and potential brain damage.

Trial Registration: ACTRN12614001263684

Trial website: http://www.liggins.auckland.ac.nz/en/about/research-themes/life-path_1/clinical-research-1_1/hpod-study.html

Recruiting Sites: Auckland City, Waitakere, North Shore, Hastings Memorial, Tauranga, Whakatane, Waikato, Invercargill

Contact for information: hpod@auckland.ac.nz

Cohort Studies included:  Yes


HINT2

This randomised trial is investigating the use of computer modelling in preterm babies to assist with the prescribing of insulin in hyperglycaemic preterm babies to avoid hypoglycaemia. Babies born <30 weeks or <1500g at birth who develop hyperglycaemia (≥10mmol/L) are eligible to participate.

Trial Registration: ACTRN12614000492651

Trial website: http://www.liggins.auckland.ac.nz/en/about/research-themes/life-path_1/clinical-research-1_1/hint_1.html

Recruiting Sites: Middlemore, Auckland City

Contact for information: k.williamson@auckland.ac.nz

Cohort Studies included:  No


The My Baby’s Movements Trial


This stepped wedge cluster randomised controlled trial will include 27 hospitals across New Zealand and Australia and include 250 000+ births over three years. The MBM package of interventions includes a mobile phone software program designed to increase maternal awareness of fetal movements and reduce delay in reporting of decreased fetal movements and an education program for clinicians around the use of MBM and best-practice management of women reporting decreased fetal movements. The aim is to assess whether the MBM package reduces the incidence of stillbirth after 28 weeks gestation. This trial has been endorsed by the PSANZ IMPACT Network.

Trial Registration: ACTRN12614000291684

Trial website: https://impact.psanz.com.au/clinical-trials/mbm-trial-information/

Recruiting Sites: Auckland City, Christchurch Women’s, Middlemore

Contact for information: mbmtrial@mater.uq.edu.au

Cohort Studies included:  No


The PAEAN Trial


This is a randomised placebo-controlled trial comparing erythropoietin and placebo in term or near term infants (≥35+0 weeks gestation) with hypoxic ischaemic encephalopathy who are receiving, or planned to receive hypothermia. The primary outcome is a composite measure of death or moderate/severe disability.

Trial Registration: ACTRN12614000669695

Trial website: https://ctc.usyd.edu.au/public-trial-pages/paean/about-paean.aspx

Recruiting Sites: Auckland City, Middlemore, Waikato

Contact for information: paean@ctc.usyd.edu.au

Cohort Studies included:  No


The ProViDE Study


This randomised trial will investigate whether providing extra protein in the first 5 days after birth will improve neurodevelopmental outcomes and growth in extremely low birthweight babies (<1000g) measured at 2 years corrected age.

Trial Registration: ACTRN12612001084875

Trial website: https://impact.psanz.com.au/clinical-trials/provide-trial-information/

Recruiting Sites: Auckland City, Middlemore, Waikato, Wellington, Christchurch Women’s, Dunedin

Contact for information: BCormack@adhb.govt.nz

Cohort Studies included:  Yes


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